Building Strategic Partnerships

Strategic Support for Breakthrough Therapies

Client: A biotech company located outside the US mainland.

Challenge: The company had purified an active compound from a natural plant source with promising anti-cancer activities and sought to develop it into an orally available drug. However, they needed closer connections with biotech hubs on the US mainland, as well as partnerships with companies specializing in medicinal chemistry, chemical synthesis, and toxicity testing to advance the development of their lead compound.

GOTBio’s Solution:

• Connecting to Key Expertise: GOTBio leveraged its extensive network to connect the company with top-tier medicinal chemists in the United States. These connections resulted in a crucial partnership that allowed for the design and optimization of the company’s lead compound.
• Strategic Preclinical Development: GOTBio provided a comprehensive strategic plan for the preclinical development of the newly designed lead molecules. This plan included:
  • Securing contracts with trusted Contract Research Organizations (CROs) specializing in:
    • Chemical synthesis
    • In vitro and in vivo efficacy testing
    • Toxicity testing
    • Preclinical animal studies
    • Pharmacokinetics (PK) and Absorption, Distribution, Metabolism, and Excretion (ADME) determinations.

Outcome:

• The strategic partnerships established through GOTBio’s connections, along with the successful execution of the preclinical testing plan, resulted in the development of a promising orally available anti-cancer drug. The company was able to rapidly move forward with their compound, positioning themselves for further clinical development and potential market success.